Sun setting between saguaros in the Sonoran Desert near Phoenix

An Amazing San Diego to Phoenix Road Trip

Published by Lora Purennet on January 29 2024

Get ready to set off on a drive from the sandy shores of the Pacific Ocean to the cacti-laden landscapes of Arizona. This road trip from San Diego to Phoenix will take you past stunning landscapes, roadside Americana, and some of the most beautiful sunsets you will get to enjoy in your lifetime.

You can do this 400-mile road trip from Sn Diego to Phoenix in 6 hours and 40 minutes. On the way, you can stop at Yucca Valley, Temecula, Palm Springs, Joshua Tree National Park, Yuma, Kofa National Wildlife Refuge and Cleveland National Forest.

To top it all off, this road trip is full of American desert culture and plenty of quirky landmarks to enjoy. Continue reading below to learn about the best routes, each route's pros and cons, where to stay, the best seasons to drive, and the incredible highlights to see along the way.

Where is Phoenix and how far is a road trip from San Diego?

Phoenix, Arizona is located in southern Arizona, deep in the American Southwest. It is famous as a destination with nice weather and plenty of sunshine.

There are two routes that take you from the beaches and ocean views of San Diego, California, to the desert vistas and historic towns along the way to Phoenix, Arizona.

Skyline of downtown Phoenix, Arizona with mountains in the background
Phoenix is a beautiful desert city in Arizona, and is a fantastic destination to visit from San Diego.
Sean Pavone/Shutterstock.com

The Palm Springs Route has an eclectic mix of Californian cities and desert towns, guiding you through places like Escondido, Temecula, and Palm Springs. A brief detour takes you to Joshua Tree National Park, one of the most iconic national parks in the USA.

This route, stretching over 400 miles with a drive time of approximately 6 hours and 40 minutes, is perfect for a 3-day journey.

The Yuma Route will take you through lush forested areas and romantic stretches of open desert. Starting from El Cajon, you'll wind through Pine Valley, the serene Cleveland National Forest, and El Centro, reaching the historic town of Yuma.

This trip is a 360-mile journey you can complete in about 4 hours and 40 minutes. We recommend making this a 2-day getaway to really experience the contrasting landscapes and cultural richness of Southern California and Arizona.

As you reach Phoenix, the nightlife, desert vistas, and rich cultural heritage await. Known for its warm weather and stunning sunsets, Phoenix is a treasure trove of experiences, from its popular food scene to its thriving arts and culture.

How long is the road trip from San Diego to Phoenix, and how many days will it take?

Comparing road trip routes from San Diego to Phoenix
RouteDistanceDriving TimeRecommended Days
Yuma Route360 miles4 hours 40 minutes2 Days
Palm Springs Route400 miles6 hours 40 minutes3 Days

What is the best road trip route from San Diego to Phoenix?

There is no best route for a road trip from San Diego to Phoenix. That being said, this is how our two routes stack up against each other, looking at some factors that might influence your decision.

San Diego to Phoenix - which route is best for you?
Palm Springs RouteYuma Route
Easy Driving⭐️⭐️⭐️⭐️⭐️⭐️⭐️⭐️⭐️
Scenery⭐️⭐️⭐️⭐️⭐️⭐️⭐️
Facilities⭐️⭐️⭐️⭐️⭐️⭐️
Things to do⭐️⭐️⭐️⭐️⭐️⭐️⭐️
Traffic Flow⭐️⭐️⭐️⭐️⭐️⭐️⭐️⭐️

Driving from San Diego to Phoenix via Palm Springs

The Palm Springs Route has a blend of easy driving and great scenery, making it an excellent option if you want to relax while seeing some incredible sights.

Driving this route is a breeze, thanks to the smooth sailing along CA-79 and the interstates. This route is a mostly stress-free experience, allowing you to focus on the beautiful landscapes.

A majestic Joshua tree with stone hills in the background during golden hour/sunset
Palm Springs Route is a great option if you are looking for a great variety of different things to see and places to visit such as Joshua Tree National Park.
Chris Curtis/Shutterstock.com

Speaking of landscapes, the Palm Springs Route will take you through some beautiful scenery as you drive towards the desert oasis of Phoenix. You'll travel through the lush vineyards of Temecula, the stunning San Bernardino National Forest, Palm Springs, and Joshua Tree National Park.

You might be wondering whether this route has a good number of facilities. While the stretch up to Palm Springs is well-equipped with amenities, the second half is more sparse. However, you'll usually find basic comforts like regular rest stops and vending machines.

There are many things to do on this route that there will never be a dull moment. The journey is full of enticing stops that include cities like Palm Springs, wineries, and natural wonders.

Some areas of California can be notorious about traffic congestion, but you can rest easy. Aside from expected rush hour congestion and weekend crowds, traffic remains fairly fluid on the Palm Springs Route.

Driving from San Diego to Phoenix via Yuma

The Yuma Route from San Diego to Phoenix is a straightforward drive that will take you through beautiful desert scenery and charming small towns.

As we mentioned above, this is a pretty easy drive. Following primarily two interstates first to Yuma and then to Phoenix, the journey has well-maintained roads and clear signs, making it a hassle-free drive.

Highway with saguaro cacti lining either side, leading to White Tank Mountain Park
While you might not have national parks to visit on the Yuma Route, your drive will be surrounded by beautiful views of the Sonoran Desert.
Karen Grigoryan/Shutterstock.com

While the Yuma Route may lack the diversity of coastal or mountainous landscapes, the Sonoran Desert and mountain views are incredible and you will get to enjoy these views for most of the drive.

While cities like Yuma have plenty of gas stations, dining, and lodging, be prepared for fewer amenities in the more secluded desert areas. Planning is key to ensure comfort throughout these stretches.

Though it may not have as many attractions as the alternative route, Yuma's historical sites, like the Yuma Territorial Prison State Historic Park, are great to visit. A highlight if you love off-road adventures is the Imperial Sand Dunes Recreation Area.

Traffic flow on this route is generally smooth. Outside of peak times, you can expect an uninterrupted drive. While Yuma might experience some congestion and delays, these are typically short-lived and don't significantly slow you down.

Driving Route from San Diego to Phoenix

So, you have decided which route is the best for you on a road trip from San Diego to Phoenix and want to learn more about how to follow this drive and where it will take you.

You will find high-level directions for each route below. However, always consult GPS to make sure you are on the right track as you make your way to Phoenix.

Driving the Palm Springs Route

Start the Palm Springs Route by leaving San Diego via Interstate 15 (I-15) N, cruising towards Escondido. As you approach Temecula, consider making a stop to explore the historical and cultural charm of Temecula Old Town.

Continue on I-15 N and merge onto CA-79 N towards Diamond Valley Lake, an idyllic spot for nature enthusiasts, before veering onto the I-10 E. On your way, make sure to visit the Cabazon Dinosaurs, a quirky and iconic roadside attraction that you can't miss.

Soon, you'll arrive in the city of Palm Springs. For breathtaking panoramic views, take a trip up the Palm Springs Aerial Tramway to Mount San Jacinto State Park.

Continuing east on the I-10, make a slight detour north on CA-62 to visit the eclectic Desert Christ Park in Yucca Valley. Further along CA-62, you'll enter the entrance of Joshua Tree National Park.

Return to the route, continue on the I-10 E, and make a brief stop at the quirky Rice Desert Signpost. As you near the Arizona border, consider a detour south on US-95 to explore the unspoiled wilderness of the Kofa National Wildlife Refuge.

Finally, as you approach Phoenix, take a moment to enjoy the beauty of White Tank Mountain Regional Park, a fitting end this amazing road trip.

Cabazon Dinosaur statue stands tall next to a Burger King restaurant in California, with desert mountains behind
Cabazon Dinosaurs are great roadside attractions on the Palm Springs Route, especially if you are traveling with family.
Attila Adam/Shutterstock.com

Driving the Yuma Route

Begin your journey on the Yuma Route by departing San Diego along I-8 E, making your way towards the Cleveland National Forest. This area, known for its winding roads and breathtaking vistas, offers plenty of nature.

As you continue eastward, take a moment to explore the Alpine Historical Society Museum, located just off the I-8. Further along, the wildlife sanctuary Lions Tigers and Bears provides a unique opportunity to encounter exotic animals and learn about them.

Venture further into the mountains by taking the Sunrise Scenic Byway. Then, descend into the rugged Imperial Valley and visit the Imperial Valley Desert Museum.

As you approach the city of Yuma, located on the banks of the Colorado River, make a stop at the Museum of History in Granite, Felicity, a unique artistic and historical project.

From Yuma, head north to explore Martinez Lake and the Imperial National Wildlife Refuge to see wild animals in their natural habitat.

As you journey towards Phoenix, consider a detour to the Painted Rock Petroglyph Site and Campground to see ancient art etched in stone. Then, visit Skyline Regional Park in Arizona, a natural playground for outdoor activities, before reaching Phoenix.

Fishing piers on lake on a sunny day
If you'd like to admire different landscapes after driving in the desert for so long, Martinez Lake will be a refreshing treat.
KDzPloch/Shutterstock.com

Where to stop overnight on a road trip between San Diego and Phoenix

Because of all the sights and highlights along the way on a San Diego to Phoenix road trip, we recommend staying in one of the incredible destinations below. This way, you'll not only stay rested, but have time to enjoy this wonderful part of the USA.

A luxurious stay in Palm Springs

Nestled halfway along The Palm Springs Route, the city of Palm Springs is like nowhere else in the country. Known for its stunning mid-century modern architecture, luxurious resorts and Mount San Jacinto, Palm Springs is the perfect stopover.

This desert city is a slice of Hollywood glamor set against rugged mountains and open skies. Here, the "Forever Marilyn" statue towers 26 feet high, capturing the iconic pose of Marilyn Monroe from "The Seven Year Itch.”

A giant Marilyn Monroe statue called "Forever Marilyn" in between the palm trees on a sunny day
Forever Marilyn" will welcome you to Palm Springs, where you can get the celebrity treatment yourself!
Michael Vi/Shutterstock.com

As the sun sets, we recommend retreating to the exquisite L'Horizon Resort & Spa. This luxurious hideaway is renowned for its individually designed bungalows, each offering a private and personalized retreat that's as stylish as it is secluded.

The resort sits against a beautiful mountain backdrop, artfully illuminated at night, making it super romantic and peaceful. On top of it all, you'll be treated to various experiences and amenities. Relax in the spa and hot tub, or take a leisurely bicycle ride, courtesy of the resort, to explore the city's enchanting streets.

While in Palm Springs, make sure to stroll down the Walk of the Stars, Palm Springs, explore the fascinating exhibits at the Palm Springs Air Museum, or venture into the wilds of the Coachella Valley Preserve.

And for an experience that elevates your trip, take the Palm Springs Aerial Tramway to the heights of Mount San Jacinto, where breathtaking views and crisp mountain air await.

River views in sunny Yuma

The historic city of Yuma is an ideal stopover on the route that shares its name, 2 hours and 40 minutes into the drive. Famous for its sunshine and prime location along the Colorado River, Yuma offers plenty of activities, from water sports to nature walks by the river.

Yuma is known as the "Winter Vegetable Capital of the World." With its extended growing season, the city produces year-long fruits and veggies.

A steam train waiting at the crossing on a sunny day
If you love trains as much as we do, then we definitely recommend visiting Yuma Crossing National Heritage Area while visiting this city.
Marti Bug Catcher/Shutterstock.com

For your stay in Yuma, the highly-rated Radisson Hotel Yuma is the peak of comfort and luxury. This elegant hotel boasts a stunning indoor/outdoor pool and hot tub, perfect for unwinding after a day of exploration.

The on-site Market Wine Bar Bistro, nestled within the hotel, serves classic American steak and seafood entrees. Plus, the bar lounge, with its daily happy hour and specialty drinks, is the perfect setting to unwind and socialize.

During your stay, you will find plenty of places to visit in this beautiful city. Spend some time at the Colorado River State Historic Park, Yuma Crossing National Heritage Area, or explore the Yuma History Museum for the perfect afternoon, learning more about what makes Yuma special.

If you love nature, you will also find plenty of opportunity to spend some time outdoors, such as at East Wetlands Park or the Yuma Conservation Garden.

Our favorite place to stay in Phoenix

Once you arrive in Phoenix, the Arizona Biltmore A Waldorf Astoria Resort, is the perfect place to stay in the heart of the desert. This legendary hotel, known for its architecture and history, is full of excellent amenities and plenty of charm.

The resort boasts beautifully appointed rooms, seven sparkling pools, a thrilling 65-foot waterslide, seven diverse dining outlets, and two championship golf courses. Plus, you'll get to relax in the Sol Garden at Tierra Luna Spa after your drive.

The Hole-in-the-Rock natural geological formation is visible from across one of Papago Park's ponds.
Papago Park is the perfect place to visit to get away from the hustle and bustle of the city.
Gregory E. Clifford/Shutterstock.com

For a relaxing evening drink, you'll love the Spire Bar. Or, for an unforgettable meal, don't miss the delicious food of McArthur's Restaurant & Bar.

Beyond the resort's gates, Phoenix is full of cultural and natural treasures. Visit the historic Wrigley Mansion to marvel at its stunning architecture and lush gardens, and enjoy a fine dining experience.

Next, explore the Heard Museum and the Phoenix Art Museum. For outdoor enthusiasts, don't miss Papago Park and Camelback Mountain, renowned for its challenging trails and breathtaking panoramic views of the desert landscape.

Best time to travel from San Diego to Phoenix on a road trip

The drive from San Diego to Phoenix is perfect any time of the year. Below, we've included highlights during each season, so you can plan when to travel.

Traveling to Phoenix from San Diego in summer

Summer is a hot and exciting time to travel along both routes. Areas like Temecula and the Coachella Valley, often experience temperatures exceeding 100 degrees Fahrenheit.

While the summer heat intensifies the desert's stark beauty, it also means you'll need to come prepared with extra water and sun protection.

During the summer, don't miss the Stagecoach Festival. And once you reach Phoenix, don't miss its air-conditioned art galleries and outdoor pools.

Traveling to Phoenix from San Diego in winter

The winter is much milder, with temperatures hovering between 50 and 70 degrees Fahrenheit. The cooler temperatures provide a pleasant backdrop for exploring the natural and cultural landmarks without the intense heat of summer.

Winter also brings unique events, such as the Gila Bend Butterfield Stage Days & Rodeo in February. Upon arrival in Phoenix, the city's winter charm is on full display, offering sunny days perfect for highlights like Papago Park or the Arizona State Fair's festivities.

Saguaros cactus in light snow with cloudy grey sky behind
You might not immediately think of snow when you are planning a drive through the Sonoran Desert, but it does snow here on occasion, creating a magical landscape.
LHBLLC/Shutterstock.com

Traveling to Phoenix from San Diego in the shoulder seasons

The shoulder seasons of spring and fall are often considered the ideal times for a road trip from San Diego to Phoenix. During these months, the weather is warm and pleasant.

The landscape blooms in spring and transforms with fall colors in the mountains. In areas like Coachella Valley, spring brings blooming deserts and the famous Coachella Music Festival in April.

Similarly, fall in Phoenix welcomes you with outdoor activities and events in comfortably cool temperatures.

The best things to see and do on a road trip from San Diego to Phoenix

Although both routes on a San Diego to Phoenix road trip are relatively short, there are plenty of incredible highlights and experiences to enjoy along the way. To help you plan your ultimate road trip, we've included our favorites below.

On the Palm Springs Route

Temecula Old Town: A charming, historic district filled with antique shops, unique boutiques, and fine dining.

Diamond Valley Lake: A stunning reservoir known for its recreational fishing, boating, and a 21.8-mile scenic trail surrounding the lake, perfect for hiking, biking, and wildlife observation.

Cabazon Dinosaurs: An iconic roadside attraction featuring enormous, lifelike dinosaur sculptures, including a gift shop inside a dinosaur's belly and an interactive dinosaur garden.

Palm Springs Air Museum: A living history museum dedicated to the preservation of America's legendary combat aircraft and pilots, offering up-close experiences and educational exhibits.

The Living Desert Zoo and Gardens: A unique zoo and botanical garden that focuses on the deserts of the world, with desert flora, fauna, and live animal shows.

Meerkat standing behind a log in the zoo
If you are traveling with family, or simply would like to learn more about desert flora and fauna, then we highly recommend visiting Living Desert Zoo and Gardens.
Cheri Alguire/Shutterstock.com

Mount San Jacinto Park: A majestic state park known for its breathtaking mountain scenery, extensive hiking trails, and the famous Palm Springs Aerial Tramway that provides stunning panoramic views.

Desert Christ Park: A tranquil outdoor park featuring over 40 large white statues depicting scenes from the Bible, set against a backdrop of the Mojave Desert's natural beauty.

Joshua Tree National Park: A vast national park celebrated for its otherworldly landscapes, fascinating rock formations, and iconic Joshua trees, perfect for hikers, climbers, and nature lovers.

Rice Desert Signpost: A quirky and remote roadside attraction marked by a signpost adorned with shoes, creating a unique photo opportunity in the middle of the desert.

Kofa National Wildlife Refuge: A pristine natural sanctuary dedicated to protecting the desert bighorn sheep and other native wildlife, offering rugged wilderness for hiking, camping, and wildlife photography.

White Tank Mountain Regional Park: A sprawling regional park boasting beautiful mountain ranges, a variety of hiking and biking trails, and ancient petroglyphs, nestled in the Sonoran Desert.

On the Yuma Route

Cleveland National Forest: A vast expanse of protected land offering a variety of outdoor activities such as hiking, camping, and wildlife viewing amidst its beautiful mountainous landscape.

Alpine Historical Society Museum: A local gem preserving the rich history of Alpine and its surroundings, showcasing artifacts, photographs, and stories in a charming, historic setting.

Lions Tigers and Bears: A premier animal sanctuary focusing on the rescue and care of big cats and other exotic animals, offering educational tours and unique animal encounters.

Sunrise Scenic Byway: A picturesque route winding through the Southern California landscape, offering breathtaking views, especially at sunrise, and access to recreational activities.

Imperial Valley Desert Museum: A cultural and natural history museum dedicated to the preservation and education of the Imperial Valley's desert environment, featuring exhibits, artifacts, and interactive displays.

Petroglyphs on round rocks piled together in the desert
Painted Rock Petroglyph Site and Campground will be a fascinating place to visit for any history buff.
C Belt/Shutterstock.com

Museum of History in Granite, Felicity: A unique outdoor museum etching historical events and memories into solid granite monuments, creating a lasting testament to human history.

Yuma Territorial Prison State Historic Park: A historic park housing the remains of the infamous Yuma Territorial Prison, offering insights into the lives of the inmates and the history of the region.

Martinez Lake: A serene desert oasis offering recreational activities such as boating, fishing, and wildlife viewing in a picturesque setting near Yuma.

Imperial National Wildlife Refuge: A sanctuary for wildlife and a haven for outdoor enthusiasts, providing opportunities for bird-watching, hiking, and exploring diverse habitats along the Colorado River.

Painted Rock Petroglyph Site and Campground: An ancient archaeological site featuring a vast collection of Native American petroglyphs, alongside camping facilities set amidst the serene desert landscape.

Skyline Regional Park: A scenic park offering a range of outdoor activities including hiking, mountain biking, and horseback riding, with trails providing stunning views of the surrounding desert and mountains.

Sonoran Desert National Monument: A magnificent protected area preserving the pristine Sonoran Desert landscape, known for its unique plant and animal life, extensive hiking trails, and significant cultural heritage.